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Product Name Human FGFR3 Antibody (LY3076226, Research Use)
Catalog Number NBR-0176
Alias/Synonyms ACH; CD333; CEK2; JTK4
Appearance Transparent Liquid
Molecule Weight 150kDa
CAS N/A
Solubility Water, PBS, TBS Buffer,etc.
Storage Temp. -80℃
Shelf Life see COA
Additional info 1 CHO Expressed
Additional info 2 Ab. Isotype - IgG
Catalog Numbe Size Price Inventory Level  
NBR-0176-100UG 100ug $95 Inquire
NBR-0176-1MG 1mg $650 Inquire
NBR-0176-5MG 5mg $1395 Inquire



【Introduction】
Product Name: Human FGFR3 Antibody (LY3076226, Research Use)
Catalog Number: NBR-0176
Target Name: FGFR3
Trade Name: LY3076226
Antibody Drug Description: LY3076226 is an antibody-drug conjugate (ADC) comprising a fully human anti-FGFR3 antibody, IMC-D11, conjugated to a cytotoxic payload, the maytansine-derivative DM4, via a cleavable linker (sulfo-SPDB).

【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

 
【Gene Information】
Gene Name: FGFR3
Synonyms: ACH; CD333; CEK2; JTK4
Target Description: FGFR3 (Fibroblast Growth Factor Receptor 3) is a Protein Coding gene. Diseases associated with FGFR3 include Achondroplasia and Hypochondroplasia. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and GPCR Pathway. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is FGFR2.
Ensembl: ENSG00000068078 
Uniprot: P22607
 
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