
【Introduction】
Product Name: Human FLT3 Antibody (IMC-EB10, Research Use)
Catalog Number: NBR-0180
Target Name: FLT3
Trade Name: IMC-EB10
Antibody Drug Description: IMC-EB10 is an anti-FLT3 monoclonal antibody, prolongs survival and reduces nonobese diabetic/severe combined immunodeficient engraftment of some acute lymphoblastic leukemia cell lines and primary leukemic samples.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: FLT3
Synonyms: CD135; FLK2; STK1
Target Description: FLT3 (Fms Related Receptor Tyrosine Kinase 3) is a Protein Coding gene. Diseases associated with FLT3 include Leukemia, Acute Myeloid and Acute Myeloid Leukemia With Minimal Differentiation. Among its related pathways are crenolanib-resistant FLT3 mutants and GPCR Pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein kinase activity. An important paralog of this gene is KDR.
Ensembl: ENSG00000122025
Uniprot: P36888