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Product Name Human GCGR Antibody (Crotedumab, Research Use)
Catalog Number NBR-0182
Alias/Synonyms GGR
Appearance Transparent Liquid
Molecule Weight 150kDa
CAS N/A
Solubility Water, PBS, TBS Buffer,etc.
Storage Temp. -80℃
Shelf Life see COA
Additional info 1 CHO Expressed
Additional info 2 Ab. Isotype - IgG
Catalog Numbe Size Price Inventory Level  
NBR-0182-100UG 100ug $95 Inquire
NBR-0182-1MG 1mg $650 Inquire
NBR-0182-5MG 5mg $1395 Inquire



【Introduction】
Product Name: Human GCGR Antibody (Crotedumab, Research Use)
Catalog Number: NBR-0182
Target Name: GCGR
Trade Name: Crotedumab
Antibody Drug Description: Crotedumab (REGN1193) (INN) is a humanized monoclonal antibody designed for the treatment of diabetes.

【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

 
【Gene Information】
Gene Name: GCGR
Synonyms: GGR
Target Description: GCGR (Glucagon Receptor) is a Protein Coding gene. Diseases associated with GCGR include Mahvash Disease and Hypoglycemia. Among its related pathways are Activation of cAMP-Dependent PKA and GPCR downstream signalling. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and guanyl-nucleotide exchange factor activity. An important paralog of this gene is GIPR.
Ensembl: ENSG00000215644
Uniprot: P47871
 
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