
【Introduction】
Product Name: Human GCGR Antibody (Volagidemab, Research Use)
Catalog Number: NBR-0183
Target Name: GCGR
Trade Name: Volagidemab
Antibody Drug Description: Volagidemab (formerly REMD 477) is a fully human antibody that specifically binds to and blocks the glucagon receptor functions, being developed by REMD.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: GCGR
Synonyms: GGR
Target Description: GCGR (Glucagon Receptor) is a Protein Coding gene. Diseases associated with GCGR include Mahvash Disease and Hypoglycemia. Among its related pathways are Activation of cAMP-Dependent PKA and GPCR downstream signalling. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and guanyl-nucleotide exchange factor activity. An important paralog of this gene is GIPR.
Ensembl: ENSG00000215644
Uniprot: P47871