Product Name: Human GITR Antibody (Ragifilimab, Research Use)
Catalog Number: NBR-0186
Target Name: GITR
Trade Name: Ragifilimab
Antibody Drug Description: Ragifilimab is an anti-human glucocorticoid-induced tumor necrosis factor receptor (tumor necrosis factor superfamily, member 18; TNFRSF18; GITR; CD357) agonistic humanized monoclonal antibody, with potential immune checkpoint modulating activity. Ragifilimab binds to and activates GITRs found on multiple types of T cells. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: GITR
Synonyms: 
Target Description: TNFRSF18 (TNF Receptor Superfamily Member 18) is a Protein Coding gene. Diseases associated with TNFRSF18 include Immunodysregulation, Polyendocrinopathy, And Enteropathy, X-Linked and Diverticulitis. Among its related pathways are Gene expression (Transcription) and Akt Signaling. Gene Ontology (GO) annotations related to this gene include tumor necrosis factor receptor activity. An important paralog of this gene is TNFRSF21.
Ensembl: ENSG00000010310
Uniprot: P48546