
【Introduction】
Product Name: Human GPNMB Antibody (Glembatumumab, Research Use)
Catalog Number: NBR-0190
Target Name: GPNMB
Trade Name: Glembatumumab
Antibody Drug Description: Glembatumumab vedotin (also known as CDX-011 and CR011-vcMMAE) is an antibody-drug conjugate (ADC) that targets cancer cells expressing transmembrane glycoprotein NMB (GPNMB).
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: GPNMB
Synonyms: HGFIN; NMB
Target Description: GPNMB (Glycoprotein Nmb) is a Protein Coding gene. Diseases associated with GPNMB include Amyloidosis, Primary Localized Cutaneous, 3 and Lichen Amyloidosis. Among its related pathways are Signaling by PTK6 and Signal Transduction. Gene Ontology (GO) annotations related to this gene include heparin binding and integrin binding. An important paralog of this gene is PMEL.
Ensembl: ENSG00000136235
Uniprot: Q14956