Product Name: Human GPR49 Antibody (BNC101, Research Use)
Catalog Number: NBR-0191
Target Name: GPR49
Trade Name: BNC101
Antibody Drug Description: BNC101 is a first-in-class humanised monoclonal antibody that targets cancer stem cells (CSC). BNC101 binds to a receptor that is overexpressed on CSC in solid tumours including colorectal, breast, pancreatic, ovarian, lung, liver and gastric cancers. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: GPR49
Synonyms: LGR5; FEX; GPR49; GPR67; HG38
Target Description: LGR5 (Leucine Rich Repeat Containing G Protein-Coupled Receptor 5) is a Protein Coding gene. Diseases associated with LGR5 include Ankyloglossia With Or Without Tooth Anomalies and Mucositis. Among its related pathways are Signaling by WNT and ncRNAs involved in Wnt signaling in hepatocellular carcinoma. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is LGR6.
Ensembl: ENSG00000139292
Uniprot: O75473