Product Name: Human GPR49 Antibody (Petosemtamab, Research Use)
Catalog Number: NBR-0192
Target Name: GPR49
Trade Name: Petosemtamab
Antibody Drug Description: Petosemtamab is an anti-EGFRxLGR5 bispecific antibody, designed to bind cancer stem cells that express leucine-rich repeat-containing G protein-coupled receptor. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: GPR49
Synonyms: LGR5; FEX; GPR49; GPR67; HG38
Target Description: LGR5 (Leucine Rich Repeat Containing G Protein-Coupled Receptor 5) is a Protein Coding gene. Diseases associated with LGR5 include Ankyloglossia With Or Without Tooth Anomalies and Mucositis. Among its related pathways are Signaling by WNT and ncRNAs involved in Wnt signaling in hepatocellular carcinoma. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is LGR6.
Ensembl: ENSG00000139292
Uniprot: O75473