Product Name: Human IGF-1R Antibody (Teprotumumab, Research Use)
Catalog Number: NBR-0209
Target Name: IGF-1R
Trade Name: Teprotumumab
Antibody Drug Description: Teprotumumab is a fully human monoclonal antibody that binds to the ligand binding extracellular alpha subunit of the IGF-1R (Figure 2). Formerly known as R1507, teprotumumab was first developed and studied with regards to its use for cancer therapy, but has fallen short of making significant differences in prognosis in multiple studies. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: IGF-1R
Synonyms: CD221; IGFIR; IGFR; JTK13; MGC18216
Target Description: Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. 
Ensembl: ENSG00000140443
Uniprot: P08069