Product Name: Human IL-1RL2 Antibody (Spesolimab, Research Use)
Catalog Number: NBR-0215
Target Name: IL-1RL2
Trade Name: Spesolimab
Antibody Drug Description: Spesolimab is a novel, humanized, selective antibody that blocks the activation of the interleukin-36 receptor (IL-36R), a signaling pathway within the immune system shown to be involved in the pathogeneses of several autoimmune diseases, including GPP. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: IL-1RL2
Synonyms: IL1R-rp2; IL1RRP2
Target Description: Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity).
Ensembl: ENSG00000115598 
Uniprot: Q9HB29