
【Introduction】
Product Name: Human IL-1RL2 Antibody (Imsidolimab, Research Use)
Catalog Number: NBR-0216
Target Name: IL-1RL2
Trade Name: Imsidolimab
Antibody Drug Description: Imsidolimab, previously known as ANB019, is an antibody that inhibits the function of the interleukin-36-receptor, or IL-36R, which we are developing as a potential first-in-class therapy for patients suffering from generalized pustular psoriasis (GPP) and moderate-to-severe hidradenitis suppurativa.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: IL-1RL2
Synonyms: IL1R-rp2; IL1RRP2
Target Description: Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity).
Ensembl: ENSG00000115598
Uniprot: Q9HB29