Product Name: Human IL-23 Antibody (Guselkumab, Research Use)
Catalog Number: NBR-0220
Target Name: IL-23
Trade Name: Guselkumab
Antibody Drug Description: Guselkumab is a human immunoglobulin G1 lambda (IgG1λ) monoclonal antibody that selectively blocks interleukin-23. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: IL-23
Synonyms: IL-23; IL-23A; IL23P19; P19; SGRF
Target Description: Associates with IL12B to form the pro-inflammatory cytokine IL-23 that plays different roles in innate and adaptive immunity. Released by antigen-presenting cells such as dendritic cells or macrophages, binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R to activate JAK2 and TYK2 which then phosphorylate the receptor to form a docking site leading to the phosphorylation of STAT3 and STAT4.
Ensembl: ENSG00000110944 
Uniprot: Q9NPF7