Product Name: Human IL-33 Antibody (Etokimab, Research Use)
Catalog Number: NBR-0225
Target Name: IL-33
Trade Name: Etokimab
Antibody Drug Description: Etokimab, an IL-33 inhibitor, did not achieve statistically significant improvement in a Phase II trial for patients suffering from chronic rhinosinusitis with nasal polyps. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: IL-33
Synonyms: C9orf26; DKFZp586H0523; DVS27; IL1F11; NF-HEV
Target Description: Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines.
Ensembl: ENSG00000137033
Uniprot: O95760