【Introduction】
Product Name: Human LOXL2 Antibody (Simtuzumab, Research Use)
Catalog Number: NBR-0239
Target Name: LOXL2
Trade Name: Simtuzumab
Antibody Drug Description: Simtuzumab (INN; formerly GS 6624) is a humanized monoclonal antibody designed for the treatment of fibrosis. It binds to LOXL2 and acts as an immunomodulator.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: LOXL2
Synonyms: LOR; WS9-14
Target Description: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
Ensembl: ENSG00000134013
Uniprot: Q9Y4K0