【Introduction】
Product Name: Human MERTK Antibody (RGX-019, Research Use)
Catalog Number: NBR-0244
Target Name: MERTK
Trade Name: RGX-019
Antibody Drug Description: RGX-019 is a novel humanized MerTK targeting monoclonal antibody with a unique mechanism of action.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: MERTK
Synonyms: c-Eyk; mer; RP38; Tyro12
Target Description: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6. Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis).
Ensembl: ENSG00000153208
Uniprot: Q12866