Product Name: Human Nogo-A Antibody (Ozanezumab, Research Use)
Catalog Number: NBR-0258
Target Name: Nogo-A
Trade Name: Ozanezumab
Antibody Drug Description: Ozanezumab is a monoclonal antibody designed for the treatment of ALS and multiple sclerosis.Ozanezumab targets a protein called Neurite Outgrowth Inhibitor (NOGO-A) or Reticulon 4. NOGO-A is a protein that in humans is encoded by the RTN4 gene that has been identified as an inhibitor of neurite outgrowth specific to the central nervous system. NOGO-A is found at higher than normal levels in persons with MND. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: Nogo-A
Synonyms: ASY; KIAA0886; NOGO; NSP-CL
Target Description: Immune inhibitory receptor involved in self-nonself discrimination. In complex with KLRD1 on cytotoxic and regulatory lymphocyte subsets, recognizes non-classical major histocompatibility (MHC) class Ib molecule HLA-E loaded with self-peptides derived from the signal sequence of classical MHC class Ia molecules. 
Ensembl: ENSG00000115310
Uniprot: Q9NQC3