
【Introduction】
Product Name: Human PDGFRA Antibody (Tovetumab, Research Use)
Catalog Number: NBR-0265
Target Name: PDGFRA
Trade Name: Tovetumab
Antibody Drug Description: Tovetumab is an anti-PDGFRa monoclonal antibody designed for the treatment of cancer. It was developed by MedImmune, and trialed for use in glioblastoma and non-small cell lung cancer.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: PDGFRA
Synonyms: CD140a; GAS9; PDGFR2
Target Description: Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration.
Ensembl: ENSG00000134853
Uniprot: P16234