
【Introduction】
Product Name: Human PVRIG Antibody (GSK4381562, Research Use)
Catalog Number: NBR-0272
Target Name: PVRIG
Trade Name: GSK4381562
Antibody Drug Description: GSK4381562 is a differentiated anti-PVRIG antibody and represents a new therapeutic approach designed to enhance NK and T cell activation in the tumor microenvironment.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: PVRI
Synonyms: GC7orf15; CD112R; MGC2463
Target Description: Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.
Ensembl: ENSG00000213413
Uniprot: Q6DKI7