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Product Name Human RANKL Antibody (Denosumab, Research Use)
Catalog Number NBR-0275
Alias/Synonyms CD254; ODF; OPGL; RANKL; TRANCE
Appearance Transparent Liquid
Molecule Weight 150kDa
CAS N/A
Solubility Water, PBS, TBS Buffer,etc.
Storage Temp. -80℃
Shelf Life see COA
Additional info 1 CHO Expressed
Additional info 2 Ab. Isotype - IgG
Catalog Numbe Size Price Inventory Level  
NBR-0275-100UG 100ug $95 Inquire
NBR-0275-1MG 1mg $650 Inquire
NBR-0275-5MG 5mg $1395 Inquire



【Introduction】
Product Name: Human RANKL Antibody (Denosumab, Research Use)
Catalog Number: NBR-0275
Target Name: RANKL
Trade Name: Denosumab
Antibody Drug Description: Denosumab injection (Xgeva) is used Denosumab injection is in a class of medications called RANK ligand inhibitors. It works to prevent bone loss by blocking a certain receptor in the body to decrease bone breakdown. It works to treat GCTB by blocking a certain receptor in the tumor cells which slows the tumor growth. It works to treat high calcium levels by decreasing bone breakdown as the breakdown of bones releases calcium.

【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

 
【Gene Information】
Gene Name: RANKL
Synonyms: CD254; ODF; OPGL; RANKL; TRANCE
Target Description: Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. 
Ensembl: ENSG00000120659 
Uniprot: O14788 
 
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