
【Introduction】
Product Name: Human Tau Antibody (Gosuranemab, Research Use)
Catalog Number: NBR-0287
Target Name: Tau
Trade Name: Gosuranemab
Antibody Drug Description: Gosuranemab is an antibody directed against the N-terminus of tau. Target engagement was demonstrated with lowering of N-terminal tau in cerebrospinal fluid (CSF), consistent with prior studies.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: Tau
Synonyms: DDPAC; FLJ31424; FTDP-17; MAPTL; MGC138549; MSTD; MTBT1; MTBT2; PPND; PPP1R103; tau
Target Description: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity . The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both.
Ensembl: ENSG00000186868
Uniprot: P10636