
【Introduction】
Product Name: Human TIM-3 / HAVCR2 Antibody (Sabatolimab, Research Use)
Catalog Number: NBR-0292
Target Name: TIM-3 / HAVCR2
Trade Name: Sabatolimab
Antibody Drug Description: Sabatolimab is a novel immuno-myeloid therapy targeting TIM-3, an immune regulator expressed on immune cells and myeloid leukemic progenitors but not on normal hematopoietic stem cells.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: TIM-3 / HAVCR2
Synonyms: CD366; FLJ14428; Tim-3; TIM3; TIMD3
Target Description: Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand.
Ensembl: ENSG00000135077
Uniprot: Q8TDQ0