【Introduction】
Product Name: Human VAP-1 Antibody (Timolumab, Research Use)
Catalog Number: NBR-0300
Target Name: VAP-1
Trade Name: Timolumab
Antibody Drug Description: Timolumab, as known as BTT1023, is a fully human, monoclonal, anti-AOC3 antibody which blocks the adhesion function of AOC3, thereby diminishing leucocyte entry into sites of tissue inflammation. This drug was developed for the treatment of Psoriasis, Rheumatoid arthritis, and Primary sclerosing cholangitis.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: VAP-1
Synonyms: HPAO; VAP-1; VAP1
Target Description: Cell adhesion protein that participates in lymphocyte extravasation and recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has semicarbazide-sensitive (SSAO) monoamine oxidase activity. May play a role in adipogenesis
Ensembl: ENSG00000131471
Uniprot: Q16853