Product Name: Human FLT1 / VEGFR1 Antibody (Icrucumab, Research Use)
Catalog Number: NBR-0301
Target Name: FLT1 / VEGFR1
Trade Name: Icrucumab
Antibody Drug Description: Icrucumab (IMC-18F1) is a human monoclonal antibody designed for the treatment of solid tumors. Icrucumab was developed by ImClone Systems Inc. It is undergoing Phase I trials. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: FLT1 / VEGFR1
Synonyms: FLT; VEGFR1
Target Description: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Acts as a positive regulator of postnatal retinal hyaloid vessel regression.
Ensembl: ENSG00000102755
Uniprot: P17948