【Introduction】
Product Name: Human Frizzled-10 Antibody (Tabituximab, Research Use)
Catalog Number: NBR-0303
Target Name: Frizzled-10
Trade Name: Tabituximab
Antibody Drug Description: Tabituximab is a radioimmunoconjugate composed of a humanized monoclonal antibody (MoAb) tabituximab barzuxetan against FZD10, with potential antineoplastic activity.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: Frizzled-10
Synonyms: CD350
Target Description: Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.
Ensembl: ENSG00000111432
Uniprot: Q9ULW2