【Introduction】
Product Name: Human IFNAR-1 Antibody (Anifrolumab, Research Use)
Catalog Number: NBR-0317
Target Name: IFNAR-1
Trade Name: Anifrolumab
Antibody Drug Description: Saphnelo (anifrolumab) is a fully human monoclonal antibody that binds to subunit 1 of the type I IFN receptor, blocking the activity of type I IFNs.4 Type I IFNs such as IFN-alpha, IFN-beta and IFN-kappa are cytokines involved in regulating the inflammatory pathways implicated in SLE.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: IFNAR-1
Synonyms: IFNAR; IFRC
Target Description: Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2.
Ensembl: ENSG00000142166
Uniprot: P17181