Product Name: Human IL-22RA Antibody (ARGX-112, Research Use)
Catalog Number: NBR-0318
Target Name: IL-22RA
Trade Name: ARGX-112
Antibody Drug Description: ARGX-112 is a novel, fully human antibody neutralizing both IL20 and IL22 signaling through blockade of their common receptor, IL22R, with low picomolar potency. IL20 and IL22 are involved in proliferation and differentiation of keratinocytes (skin cells) and when over-expressed, are implicated in autoimmune diseases of the skin, including atopic dermatitis, psoriasis and pustular psoriasis.  Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: IL-22RA
Synonyms: CRF2-9; IL22R
Target Description: Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways.
Ensembl: ENSG00000142677 
Uniprot: Q8N6P7