Product Name: Human ILT7 Antibody (Daxdilimab, Research Use)
Catalog Number: NBR-0319
Target Name: ILT7
Trade Name: Daxdilimab
Antibody Drug Description: Daxdilimab (HZN-7734) is an anti-ILT7 human monoclonal antibody that depletes certain dendritic cells. Depleting these cells may interrupt the cycle of inflammation that causes tissue damage in a variety of autoimmune conditions.  Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: ILT7
Synonyms: CD85g; ILT7
Target Description: Functions coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G 1, 2. Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades.
Ensembl: ENSG00000239961
Uniprot: P59901