Product Name: Human C3 Antibody (NGM621, Research Use)
Catalog Number: NBR-0324
Target Name: C3
Trade Name: NGM621
Antibody Drug Description: NGM621 is a humanized IgG1 monoclonal antibody engineered to potently inhibit complement C3. We believe that there are multiple possible areas of differentiation for NGM621 based on efficacy, dosing frequency and safety. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: C3
Synonyms: ARMD9; C3a; C3b; CPAMD1
Target Description: C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
Ensembl: ENSG00000125730
Uniprot: P01024