【Introduction】
Product Name: Human C1q Antibody (ANX005, Research Use)
Catalog Number: NBR-0335
Target Name: C1q
Trade Name: ANX005
Antibody Drug Description: NX005 is a humanized immunoglobulin G4 recombinant antibody against C1q that inhibits its function as the initiating molecule of the classical complement cascade. The safety and tolerability of ANX005 are currently being evaluated in a phase I trial in healthy volunteers
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: C1q
Synonyms: gC1Q-R; gC1qR; HABP1; p32; SF2p32
Target Description: Is believed to be a multifunctional and multicompartmental protein involved in inflammation and infection processes, ribosome biogenesis, protein synthesis in mitochondria, regulation of apoptosis, transcriptional regulation and pre-mRNA splicing.
Ensembl: ENSG00000108561
Uniprot: Q07021