Product Name: Human ADAMTS5 Antibody (M6495, Research Use)
Catalog Number: NBR-0340
Target Name: ADAMTS5
Trade Name: M6495
Antibody Drug Description: M6495 is an anti-catabolic, bivalent, bifunctional Nanobody® that selectively inhibits ADAMTS-5 in vitro, reducing aggrecan cleavage.. M6495 is potent anti-catabolic drug which inhibits aggrecan and type II collagen degradation in both bovine and human cartilage explant cultures and bovine synovial co-cultures. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: ADAMTS5
Synonyms: ADAMTS11; ADMP-2
Target Description: Metalloproteinase that plays an important role in connective tissue organization, development, inflammation and cell migration. Extracellular matrix (ECM) degrading enzyme that show proteolytic activity toward the hyalectan group of chondroitin sulfate proteoglycans (CSPGs) including ACAN, VCAN, BCAN and NCAN.
Ensembl: ENSG00000154736 
Uniprot: Q9UNA0