Product Name: Human IL-1B Antibody (Canakinumab, Research Use)
Catalog Number: NBR-0396
Target Name: IL-1B
Trade Name: Canakinumab
Antibody Drug Description: Canakinumab (ACZ885, Ilaris) is a human anti-IL-1β monoclonal antibody developed by Novartis. its mode of action is based on the neutralization of 1β signaling, resulting in suppression of inflammation in patients with disorders of autoimmune origin. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: IL-1B
Synonyms: IL-1B; IL1-BETA; IL1F2
Target Description: Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.
Ensembl: ENSG00000125538
Uniprot: P01584