【Introduction】
Product Name: Human CD28 Antibody (Lulizumab, Research Use)
Catalog Number: NBR-0397
Target Name: CD28
Trade Name: Lulizumab
Antibody Drug Description: Lulizumab pegol is a humanised PEGylated anti-CD28 antibody-based biologic, developed as a potential treatment for autoimmune diseases. This so-called domain antibody (dAb) contains the smallest functional binding unit and lacks the divalent structure characteristic of a complete antibody . PEGylation improves solubility and extends circulating half-life .
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: CD28
Synonyms:
Target Description: Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.
Ensembl: ENSG00000178562
Uniprot: P10747