【Introduction】
Product Name: Human Ly6E Antibody (RG7841, Research Use)
Catalog Number: NBR-0398
Target Name: Ly6E
Trade Name: RG7841
Antibody Drug Description: RG7841, also known as RG-7841, DLYE5953A and Anti-Ly6E, Lymphocyte antigen 6 complex, locus E, is an antibody-drug conjugate being developed by Genentech / Roche in collaboration with Seattle Genetic.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: Ly6E
Synonyms: RIG-E; SCA-2; TSA-1
Target Description: GPI-anchored cell surface protein that regulates T-lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR) signaling by interacting with component CD3Z/CD247 at the plasma membrane, leading to CD3Z/CD247 phosphorylation modulation (By similarity).
Ensembl: ENSG00000160932
Uniprot: Q16553