Product Name: Human uPAR Antibody (ATN-658, Research Use)
Catalog Number: NBR-0403
Target Name: uPAR
Trade Name: ATN-658
Antibody Drug Description: ATN-658, a mouse IgG1, is able to bind to D2D3 of uPAR with high affinity (Kd ∼ 1 nM), does not inhibit the binding of uPA to uPAR, and is able to bind to uPAR even when uPA was also bound. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: uPAR
Synonyms: PLAUR; CD87; URKR
Target Description: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Ensembl: ENSG00000011422
Uniprot: Q03405