【Introduction】
Product Name: Human DPEP3 Antibody (Tamrintamab, Research Use)
Catalog Number: NBR-0415
Target Name: DPEP3
Trade Name: Tamrintamab
Antibody Drug Description: Tamrintamab pamozirine, also known as SC-003, is an ADC composed of a proprietary antibody against DPEP3 (dipeptidase 3) also known as MBD3, a glycosylphosphatidylinositol anchored membrane protein from the DPEP family of dipeptidase proteins.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: DPEP3
Synonyms:
Target Description: Lacks dipeptidase activity and is unable to hydrolyze cystinyl-bis-glycine, leukotriene D4 and the beta-lactam antibiotic imipenem. The absence of activity may be due to the inability of asparagine (instead of aspartate found in DPEP1/2) at position 359 to function as the acid/base catalyst and activate the nucleophilic water/hydroxide.
Ensembl: ENSG00000141096
Uniprot: Q9H4B8