【Introduction】
Product Name: Human ETB-R Antibody (DEDN6526A, Research Use)
Catalog Number: NBR-0428
Target Name: ETB-R
Trade Name: DEDN6526A
Antibody Drug Description: DEDN6526A is an ADC with the anti-mitotic agent monomethyl auristatin (MMAE) linked to the humanized IgG1 anti-ETBR monoclonal antibody and represents a novel targeted treatment against melanoma.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: ETB-R
Synonyms: GPR37L1
Target Description: G-protein coupled receptor . Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade.
Ensembl: ENSG00000170075
Uniprot: O60883