【Introduction】
Product Name: Human EFNA4 Antibody (PF-06647263, Research Use)
Catalog Number: NBR-0433
Target Name: EFNA4
Trade Name: PF-06647263
Antibody Drug Description: PF-06647263, a novel antibody-drug conjugate consisting of an anti-EFNA4 antibody linked to a calicheamicin payload, has shown potent antitumor activity in human xenograft tumor models, including triple-negative breast cancer (TNBC).
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: EFNA4
Synonyms: EPLG4; LERK4
Target Description: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development.
Ensembl: ENSG00000243364
Uniprot: P52798