【Introduction】
Product Name: Human CD27L / CD70 Antibody (Cusatuzumab, Research Use)
Catalog Number: NBR-0434
Target Name: CD27L / CD70
Trade Name: Cusatuzumab
Antibody Drug Description: Cusatuzumab is designed as a first-in-class, high-affinity anti-CD70 monoclonal antibody with multiple intended mechanisms of action, including Fc-mediated cytotoxicity with enhanced ADCC and inhibition of CD70/CD27 signaling, resulting in killing of malignant cells such as leukemia blasts and stem cells.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: CD27L / CD70
Synonyms: CD27L; CD27LG; TNFSF7
Target Description: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
Ensembl: ENSG00000125726
Uniprot: P32970