【Introduction】
Product Name: Human FCgR3A Antibody ( AFM13, Research Use)
Catalog Number: NBR-0445
Target Name: FCgR3A
Trade Name: AFM13
Antibody Drug Description: The CD30/CD16A-bispecific antibody AFM13 is an innate immune cell engager, a first-in-class, tetravalent antibody, designed to create a bridge between CD30 on HL cells and the CD16A receptor on natural killer cells and macrophages, to induce tumor cell killing.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: FCgR3A
Synonyms: CD16; CD16a; FCG3; FCGR3
Target Description: Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG). Optimally activated upon binding of clustered antigen-IgG complexes displayed on cell surfaces, triggers lysis of antibody-coated cells, a process known as antibody-dependent cellular cytotoxicity (ADCC).
Ensembl: ENSG00000203747
Uniprot: P08637