【Introduction】
Product Name: Human C5 Antibody (Eculizumab, Research Use)
Catalog Number: NBR-0454
Target Name: C5
Trade Name: Eculizumab
Antibody Drug Description: Eculizumab is a recombinant humanized monoclonal antibody used to reduce the risk of hemolysis in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: C5
Synonyms: C5a; C5b; CPAMD4
Target Description: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.
Ensembl: ENSG00000106804
Uniprot: P01031