Product Name: Human TREM-1 Antibody (PY159, Research Use)
Catalog Number: NBR-0458
Target Name: TREM-1
Trade Name: PY159
Antibody Drug Description: PY159 is a humanized monoclonal antibody (mAb) that specifically binds Triggering receptor expressed on myeloid cells 1 (TREM1) and acts as an agonist mAb by crosslinking TREM1 and inducing downstream signaling through the TREM1/DNAX Activating Protein of 12kDa (DAP12) complex. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: TREM-1
Synonyms: CD354; TREM-1
Target Description: Cell surface receptor that plays important roles in innate and adaptive immunity by amplifying inflammatory responses. Upon activation by various ligands such as PGLYRP1, HMGB1 or HSP70, multimerizes and forms a complex with transmembrane adapter TYROBP/DAP12.
Ensembl: ENSG00000124731
Uniprot: Q9NP99