【Introduction】
Product Name: Human FcgR3a / CD16a Antibody (AFM13, Research Use)
Catalog Number: NBR-0489
Target Name: FcgR3a / CD16a
Trade Name: AFM13
Antibody Drug Description: AFM13 is a tetravalent bispecific chimeric (anti-human CD30 x anti-human CD16A) recombinant antibody construct which is being developed to treat CD30-positive malignancies.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: FcgR3a
Synonyms: CD16; CD16a; FCG3; FCGR3
Target Description: Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG). Optimally activated upon binding of clustered antigen-IgG complexes displayed on cell surfaces, triggers lysis of antibody-coated cells, a process known as antibody-dependent cellular cytotoxicity (ADCC).
Ensembl: ENSG00000203747
Uniprot: P08637