【Introduction】
Product Name: Human Amyloid Beta Antibody (GSK 933776, Research Use)
Catalog Number: NBR-0504
Target Name: Amyloid Beta
Trade Name: GSK 933776
Antibody Drug Description: GSK933776 is a humanized mouse IgG1 monoclonal antibody directed against the N-terminus of the Aβ peptide. Its Fc region has been engineered to reduce FC-receptor binding and complement activation; this was done in an effort to weaken the antibody's effector function and minimize risk of side effects such as ARIA.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: APP
Synonyms: AD1
Target Description: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis 1.
Ensembl: ENSG00000142192
Uniprot: P05067