
【Introduction】
Product Name: Human Complement C5aR1 Antibody (Avdoralimab, Research Use)
Catalog Number: NBR-0513
Target Name: Complement C5aR1
Trade Name: Avdoralimab
Antibody Drug Description: Avdoralimab (IPH 5401) is a fully human IgGκ monoclonal antibody that targets the complement C5a receptor 1 (C5aR1) that prevents its binding to C5a. Avdoralimab can be used for complement-driven inflammatory diseases and solid tumours research.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: C5AR1
Synonyms: C5A; C5AR; C5R1; CD88
Target Description: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events.
Ensembl: ENSG00000197405
Uniprot: P21730