Product Name: Human B7-H2 / ICOSL / CD275 Antibody (Prezalumab, Research Use)
Catalog Number: NBR-0526
Target Name: B7-H2 / ICOSL / CD275
Trade Name: Prezalumab
Antibody Drug Description: Prezalumab is an IgG2 type monoclonal antibody designed to bind to ICOSL, inhibiting the interaction between ICOSL and ICOS and reducing the body's autoimmune response. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: ICOSL
Synonyms: GB7-H2; B7h; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; KIAA0653
Target Description: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).
Ensembl: ENSG00000160223
Uniprot: O75144