【Introduction】
Product Name: Human BACE1 Antibody (Genentech anti-BACE1, Research Use)
Catalog Number: NBR-0529
Target Name: BACE1
Trade Name: Genentech anti-BACE1
Antibody Drug Description: The drug is a recombinant fully human anti-BACE1 monoclonal antibody, being developed by Genentech.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: BACE1
Synonyms: N/A
Target Description: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Ensembl: ENSG00000186318
Uniprot: P56817