【Introduction】
Product Name: Human TIM-3 / HAVCR2 / CD366 Antibody (Cobolimab, Research Use)
Catalog Number: NBR-0551
Target Name: TIM-3 / HAVCR2 / CD366
Trade Name: Cobolimab
Antibody Drug Description: Cobolimab is a monoclonal antibody against the inhibitory T-cell receptor, T-cell immunoglobulin and mucin domain-containing protein 3 (TIM-3), with potential immune checkpoint inhibitory and antineoplastic activities.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: HAVCR2
Synonyms: CD366; FLJ14428; Tim-3; TIM3; TIMD3
Target Description: Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand.
Ensembl: ENSG00000135077
Uniprot: Q8TDQ0