【Introduction】
Product Name: Human PTK7 / CCK4 Antibody (Cofetuzumab, Research Use)
Catalog Number: NBR-0552
Target Name: PTK7 / CCK4
Trade Name: Cofetuzumab
Antibody Drug Description: PF-06647020 (cofetuzumab pelidotin) is a humanized, anti-PTK7 antibody–drug conjugate, designed to deliver an auristatin microtubule inhibitor payload (Aur0101) into target cells. It was shown to induce prolonged tumor regression in patient-derived, tumor xenograft preclinical models.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: PTK7
Synonyms: CCK4
Target Description: Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway.
Ensembl: ENSG00000112655
Uniprot: Q13308