【Introduction】
Product Name: Human CD19 Antibody (Coltuximab, Research Use)
Catalog Number: NBR-0553
Target Name: CD19
Trade Name: Coltuximab
Antibody Drug Description: Coltuximab ravtansine (CoR) or SAR3419 is an anti-CD19 monoclonal antibody linked to the tubulin inhibitor maytansinoid DM4, which demonstrated efficacy in vitro and in vivo in ALL, as well as safety in a lymphoma phase I study.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: CD19
Synonyms: N/A
Target Description: Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens.
Ensembl: ENSG00000177455
Uniprot: P15391