Product Name: Human B7-H1 / PD-L1 / CD274 Antibody (Cosibelimab, Research Use)
Catalog Number: NBR-0563
Target Name: B7-H1 / PD-L1 / CD274
Trade Name: Cosibelimab
Antibody Drug Description: Cosibelimab is a potential best-in-class, high affinity, fully humanized monoclonal antibody of IgG1 subtype that binds directly to PD-L1 and inhibits the PD-L1 interaction with the PD-1 and B7.1 receptors. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name:  CD274
Synonyms: B7-H; B7-H1; B7H1; PD-L1; PDCD1LG1; PDL1
Target Description: Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response.
Ensembl: ENSG00000120217
Uniprot: Q9NZQ7